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mitochondria

Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

inflammaging
T cells
metformin
Autophagy

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

mitochondria
Lipids
treg
UA phase 1 study

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Nature
mitophagy
urolithin a
mitochondria
Graphical abstract of Pathogenic Th17 Cells

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

pathogenic T helper 17 cells
Th17
IL-17
Colitis
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Autophagy, Inflammation, & Metabolism Center of Biomedical Research Excellence

The AIM Center is funded by NIH grant P20GM121176, and it endows the state of New Mexico and the surrounding region with a state-of-the-art biomedical center and an intellectual and technological hub for cutting-edge research. On a larger scale, the AIM Center promises to be a nationally important center for the advancement of research on autophagy.

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