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mitophagy

figure

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

Autophagy
mitophagy
HIV

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

cardiovascular
macrophage
mTOR
mitophagy
Multidimensional mitophagy screen reveals that ANT is required for mitophagy

The ADP/ATP Translocase Drives Mitophagy Independent of Nucleotide Exchange

mitophagy
ant
nucleotide exchange
UA phase 1 study

The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

Nature
mitophagy
urolithin a
mitochondria
Graphical abstract

NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy

ALFY
Autophagy
mitophagy
NIPSNAP1
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Autophagy, Inflammation, & Metabolism Center of Biomedical Research Excellence

The AIM Center is funded by NIH grant P20GM121176, and it endows the state of New Mexico and the surrounding region with a state-of-the-art biomedical center and an intellectual and technological hub for cutting-edge research. On a larger scale, the AIM Center promises to be a nationally important center for the advancement of research on autophagy.

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