Join us at the annual AIM Center Symposium on Friday, February 22, 2019 for a day of plenary talks and workshops by leading autophagy scientists from around the world.

The symposia, hosted by Drs. Vojo Deretic (AIM Center Director), Leon Murphy (Casma Therapeutics, USA), and Li Yu (Tsinghua University, China), will take place in the Domenici Center Auditorium at the Health Sciences Center, University of New Mexico. This event will follow the 2019 Keystone autophagy meeting in Santa Fe. To register (free) for the AIM satellite symposium, click here, otherwise, click below for the full list of speakers and additional information!

A quote from senior author Dr. Eileen White "The work is significant as it provides a mechanism by which autophagy inhibition suppresses cancer growth. Most tumors obtain nutrients from the circulating blood supply and the amino acid arginine is an essential tumor nutrient. Loss of autophagy promotes the release of the enzyme arginase from the liver into the circulation, which degrades arginine, thereby suppressing tumorigenesis. What we have discovered is a means to deprive tumors of an essential nutrient."

Dr. Eileen White is at the Rutgers Cancer Institute of New Jersey, where this work comes from; she is an AIM center consultant

"We introduce for the first time a specific role for MITF in autophagy control that involves upregulation of MIR211. We show that, under stress conditions including starvation and MTOR inhibition, a MITF-MIR211 axis constitutes a novel feed-forward loop that controls autophagic activity in cells"

Read more from the AIM Center's International Council Affiliate member, Dr. Devrim Gozuacik and his group!