News

05.26.2023

The G protein-coupled oestrogen receptor GPER in health and disease: an update

Oestrogens and their receptors contribute broadly to physiology and diseases. In premenopausal women, endogenous oestrogens protect against cardiovascular, metabolic and neurological diseases and are involved in hormone-sensitive cancers such as breast cancer. Oestrogens and oestrogen mimetics mediate their effects via the cytosolic and nuclear receptors oestrogen receptor-α (ERα) and oestrogen receptor-β (ERβ) and membrane subpopulations as well as the 7-transmembrane G protein-coupled...

Expression of Interest

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for competitive mentored PI (mPI) positions to be supported by the AIM P20 NIH award. 

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Latest

09.01.2023
News

We've released a short series of videos of the 2023 AIM center openhouse workshop. Follow the AIM center's channel as we develop science content!

 

https://www.youtube.com/@aimautophagy

08.01.2023
News

Dr. Finn makes a visit to the AIM Center's science core for a tour from Dr. Deretic. Pictured is Dr. Finn alongside the AIM Center's newest instrument, the Isoplexis.   

Metabolism Corner

09.12.2023
Metabolism

The incretin system is an essential metabolic axis that regulates postprandial metabolism. The two incretin peptides that enable this effect are the glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide 1 (GLP-1), which have cognate receptors (GIPR and GLP-1R) on islet β...

09.12.2023
Metabolism

Although many novel gene-metabolite and gene-protein associations have been identified using high-throughput biochemical profiling, systematic studies that leverage human genetics to illuminate causal relationships between circulating proteins and metabolites are lacking. Here, we performed protein...

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for...