News

05.14.2019

The AIM Symposium has finished wrapping up and was by all accounts a huge success! We had leading scientist from around the world that gave wonderful talks on their current research and future plans.

05.06.2019

NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy

New research from Drs. Anne Simonsen and Terje Johansen:

The clearance of damaged or dysfunctional mitochondria by selective autophagy (mitophagy) is important for cellular homeostasis and prevention of disease. Our understanding of the mitochondrial signals that trigger their recognition and targeting by mitophagy is limited. Here, we show that

Latest

07.15.2019
Research

The AIM center executive committee and staff plus the AIM center International Council of Affiliate members (ICAM) provide a summary on the 2nd year activities that took place at the center. https:/...

05.06.2019
Research

New research from Drs. Anne Simonsen and Terje Johansen:

The clearance of damaged or dysfunctional mitochondria by selective autophagy (mitophagy) is important for cellular homeostasis and prevention...

Metabolism Corner

09.03.2019
Metabolism

Acylglycerol kinase (AGK) -triggered PTEN phosphorylation is a signaling downstream of TCR and is required for the establishment and maintenance of CD8+ T cell metabolic and functional fitness.

08.30.2019
Metabolism

BRD4, one of Bromodomain and extra-terminal domain (BET) proteins that bind to acetylated histones and transcription factors (TFs) and control cell-type-specific transcriptional programs, promotes mitochondrial fission and thereby enables asymmetric division and prostate cancer stem cell self...