News

02.01.2020

We have another round of publications from two AIM Center affiliates, both supported by the AIM Center's P20 grant!

First we have "Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes" from the AIM Center's associate director, Dr. Eric Prossnitz. If you'd like to read more, you can go here!

Second is from Dr. Vojo Deretic's postdoc, Dr. Jingyue Jia. Her new publication titled, "AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System" can be found here!

Latest

01.31.2020
Research

We have another round of publications from two AIM Center affiliates, both supported by the AIM Center's P20 grant!

First we have "Preclinical efficacy of the GPER-selective agonist G-1 in mouse...

Metabolism Corner

02.17.2020
Metabolism

Continual efferocytic clearance of apoptotic cells (ACs) by macrophages prevents necrosis and promotes injury resolution. Macrophages take up arginine and ornithine from apoptotic cells and convert them into putrescine, augmenting continual efferocytosis and resolution of atherosclerosis.

02.17.2020
Metabolism

Macrophage mTORC1 senses protein in the diet in vivo and mediates dietary protein-driven atherosclerosis and lesion complexity by regulating mitophagy and mitochondria apoptosis.

Research Opportunities at AIM

New postdoc position open in Dr. Vojo Deretic's laboratory to study Autophagy.