posted 06.11.2018 ○ News
Leptin Promotes Allergic Airway Inflammation through Targeting the Unfolded Protein Response Pathway

AIM center researchers, Drs. Meilian Liu and Xuexian Yang et all; have just published their findings in Nature - Scientific Reports on the "... previously unappreciated insight that obesity-associated hyperleptinemia contributes to enhanced pro-allergic lymphocyte responses through induction of XBP1s, leading to exacerbation of allergic asthma."

Keystone Symposium
posted 6.13.2018 ○ Article
Keystone Symposium - 2019

The Keystone Symposium on Molecular and Cellular Biology will be begin Sunday, February 17 2019 in Santa Fe, New Mexico.

Join the AIM Center in collabrative science!

For more information and registration, follow the link below!

Jingyue Jia - Abstract
posted 4.5.2018 ○ Cell Biology
Jingyue Jia -"Galectins Control mTOR in Response to Endomembrane Damage"
The AIM center's very own Jingyue Jia et al; publish exciting new research on the role of galectins in autophagy.
A brief snippet - "Gal8 inhibits mTOR activity through its Ragulator-Rag signaling machinery, whereas galectin-9 activates AMPK in response to lysosomal injury. Both systems converge upon downstream effectors including autophagy and defense against Mycobacterium tuberculosis. Thus, a novel galectin-based signal-transduction system, termed here GALTOR, intersects with the known regulators of mTOR on the lysosome and controls them in response to lysosomal damage."


4.11.2018 ○ T&F

A review by Kroemer, Galluzzi and colleagues on immune control of cancer a part of a compendium of reviews on "autophagy and inflammation" see other articles in 2018

4.12.2018 ○ T&F

Autophagy, inflammation and cancer - covered by Debnath and Monkkonen for the special issue of "autophagy and inflammation"

3.27.2018 ○ Microscopy

Monique Copeland and Paul Tillberg Explain Expansion Microscopy...

3.27.2018 ○ Nature

The immune system protects the body by responding to invading organisms. But how is an attack on useful resident microbes prevented? A pathway has now been identified that allows immune cells to sense and respond to beneficial bacteria.

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