News

03.09.2021

Autophagy in inflammation, infection, and immunometabolism

A brand new 2021 review on autophagy and immunity by Dr. Deretic. According to the author, this took a whole year to write. It's a summary of what we collectively know about autophagy and immunity with emphasis on metabolic connections and disease, honoring contributions of all those who so elegantly and stridently contributed to the field.

02.01.2020

We have another round of publications from two AIM Center affiliates, both supported by the AIM Center's P20 grant!

First we have "Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes" from the AIM Center's associate director, Dr. Eric Prossnitz. If you'd like to read more, you can go here!

Second is from Dr. Vojo Deretic's postdoc, Dr. Jingyue Jia. Her new publication titled, "AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System" can be found here!

Expression of Interest

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for competitive mentored PI (mPI) positions to be supported by the AIM P20 NIH award. 

Learn more

Latest

03.09.2021
News

A brand new 2021 review on autophagy and immunity by Dr. Deretic. According to the author, this took a whole year to write. It's a summary of what we collectively know about autophagy and immunity...

03.17.2020
News

Drs. Alison Kell and Suresh Kumar have been awarded the first two CoV2 pilot award by the AIM Center. As the world continues to rally against Covid-19, the AIM center hopes to be at the forefront of...

Metabolism Corner

07.09.2020
Metabolism

For COVID-19 and all other infectious diseases, metabolic processes are intimately connected to the mechanisms of disease pathogenesis and the resulting pathology and pathophysiology, as well as the host defence response to the infection. This article discusses why preexisting metabolic...

07.09.2020
Metabolism

Metformin improves CD4+ T cell autophagy and mitochondrial respiration, ameliorating a newly defined inflammaging profile that echoes inflammation in diabetes. Metformin-sensitive defects in immune cell autophagy accompany natural aging in people, shift mitochondrial bioenergetics, and fuel a...

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for...