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metformin

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

ESCRT
LKB1
TAK1
TOR

Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

inflammaging
T cells
metformin
Autophagy
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Autophagy, Inflammation, & Metabolism Center of Biomedical Research Excellence

The AIM Center is funded by NIH grant P20GM121176, and it endows the state of New Mexico and the surrounding region with a state-of-the-art biomedical center and an intellectual and technological hub for cutting-edge research. On a larger scale, the AIM Center promises to be a nationally important center for the advancement of research on autophagy.

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