Metabolism | Autophagy, Inflammation and Metabolism Center of Biomedical Research Excellence

Metabolism

The mitochondrial unfolded protein response inhibits pluripotency acquisition and mesenchymal-to-epithelial transition in somatic cell reprogramming

mitochondrial function

TMEM65 regulates and is required for NCLX-dependent mitochondrial calcium efflux

Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes

type 2 diabetes

T helper 1 responses

lipid peroxidation

Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. Elegans

mitochondrial genome

Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer

Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency

glucose metabolism

Futile lipid cycling: from biochemistry to physiology

PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity

Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity

glucose metabolism

histone acetylation

Mitochondrial fatty acid synthesis is an emergent central regulator of mammalian oxidative metabolism

mitochondrial fatty acid synthesis

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