Metabolism | Autophagy, Inflammation and Metabolism Center of Biomedical Research Excellence

Metabolism

Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis

Steatohepatitis

Graphical Abstract

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

immunometabolism

Graphical Abstract

STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth

Multidimensional mitophagy screen reveals that ANT is required for mitophagy

The ADP/ATP Translocase Drives Mitophagy Independent of Nucleotide Exchange

nucleotide exchange

Lipid Signaling Drives Proteolytic Rewiring of Mitochondria by YME1L

Fatty Acid Metabolites Combine with Reduced β Oxidation

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes

fatty acid oxidation

immunometabolism

Conserved functions in vertebrates

Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism

regulatory T cells

tissue homeostasis

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