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Research

Abstract diagram

ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion

Autophagy
Atg8ylation
lysosome
ATG5
Cell

Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes

Autophagy
ATG16L1
FIP200
Atg8ylation

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells

chloroquine
Azithromycin
ciprofloxacin
respiratory epithelial cells
Two new publications from the AIM Center

Another round of publications from The AIM Center!

AMPK
Metabolism
Autophagy
lysosome
Combined research images

Two new publications from the AIM Center!

galectin
Breast cancer
estrogen
GPER
AIM 2nd year editorial

Read the editorial on the AIM center in its 2nd year

AIM editorial
Graphical abstract

NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy

ALFY
Autophagy
mitophagy
NIPSNAP1
Microscope

Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance

braf
TFEB
xenograft
tgf
Graphical abstract ATG9A

ATG9A shapes the forming autophagosome through Arfaptin 2 and phosphatidylinositol 4-kinase IIIβ

Autophagy
autophagosomes
mTORC1
ATG9A
Graphical abstract of Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation

Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation

Phosphorylation
Syntaxin
17
TBK1

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Autophagy, Inflammation, & Metabolism Center of Biomedical Research Excellence

The AIM Center is funded by NIH grant P20GM121176, and it endows the state of New Mexico and the surrounding region with a state-of-the-art biomedical center and an intellectual and technological hub for cutting-edge research. On a larger scale, the AIM Center promises to be a nationally important center for the advancement of research on autophagy.

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