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Metabolism

High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy

Nature
Submitted by Lee Allers on 02.17.2020.

Macrophage mTORC1 senses protein in the diet in vivo and mediates dietary protein-driven atherosclerosis and lesion complexity by regulating mitophagy and mitochondria apoptosis.

  • cardiovascular
  • macrophage
  • mTOR
  • mitophagy
  • atherosclerosis

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