New research from Drs. Anne Simonsen and Terje Johansen:
The clearance of damaged or dysfunctional mitochondria by selective autophagy (mitophagy) is important for cellular homeostasis and...
News
"Autophagy maintains homeostasis and is induced upon stress. Yet, its mechanistic interaction with oncogenic signaling remains elusive. Here, we show that in BRAFV600E-melanoma, autophagy is induced...
Autophagy is one of the most exciting areas in biology. The 1st ISA was organized by Prof. Yoshinori Ohsumi in Okazaki (Japan) in 1997. Like previous ISAs, this symposium will cover a broad range of...
A new study in JCB by AIM International Council of Affiliates member Dr. Sharon Tooze on the still mysterious functions of ATG9.
Join us for a TAIMS presentation by Dr. Vojo Dereric as he gives a progress brief on The AIM Center!
AIM Center Pilots Mini-Presentation
Elliseo Castillo and Alexandre Chigaev
Jennifer Gillette - presenting "The Impact of Membrane Scaffolds on Hematopoietic Homeostasis and Disease"
Eva Chi - presenting "Implications of the Controlled and Selective Oxidation of Amyloid...
Published:
| FULLTEXT 03.05.2019
Syntaxin 17 (Stx17) has been implicated in autophagosome-lysosome fusion. Here, we report that Stx17 functions in assembly of protein complexes during autophagy initiation. Stx17 is phosphorylated by TBK1 whereby phospho-Stx17 controls the formation of the ATG13FIP200 mammalian pre-autophagosomal...
A new AIM Center publication by Dr. Suresh Kumar of Dr. Vojo Deretic's lab! Dr. Kumar shows the role of Syntaxin 17 in autophagy initiation.
Vojo Deretic Ph.D. gives a seminar at the Institute of Molecular and Cell Biology, Singapore on Autophagy and membrane trafficking.