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Metabolism

Graphical abstract CD8+ T cell

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment

Cholesterol
cd8
t cell
immune checkpoints
Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer

Intestinal insulin/IGF1 signalling through FoxO1 regulates epithelial integrity and susceptibility to colon cancer

Obesity
insulin
Colitis
Epithelial
Liver macrophages regulate systemic metabolism through non-inflammatory factors

Liver macrophages regulate systemic metabolism through non-inflammatory factors

liver
macrophage
metabolic
Secretion
Graphical abstract

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations

Wnt
beta-catenin
mTOR
glutamine
Graphical abstract of Pathogenic Th17 Cells

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

pathogenic T helper 17 cells
Th17
IL-17
Colitis

Pagination

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Autophagy, Inflammation, & Metabolism Center of Biomedical Research Excellence

The AIM Center is funded by NIH grant P20GM121176, and it endows the state of New Mexico and the surrounding region with a state-of-the-art biomedical center and an intellectual and technological hub for cutting-edge research. On a larger scale, the AIM Center promises to be a nationally important center for the advancement of research on autophagy.

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