The Ser/Thr protein kinase mTOR controls metabolic pathways, including the catabolic process of autophagy. Autophagy plays additional, catabolism-independent roles in homeostasis of cytoplasmic endomembranes and whole organelles. How signals from endomembrane damage are transmitted to mTOR to...
A quote from senior author Dr. Eileen White "The work is significant as it provides a mechanism by which autophagy inhibition suppresses cancer growth. Most tumors obtain nutrients from the...
"Our studies conducted in late 1990s reported on the phosphatidylinositol 3-phosphate (PI3P) mechanism of the Mycobacterium tuberculosis (Mtb) phagosome maturation block. At that time we wondered...
A new publication from Dr. Devrim Gozuacik, an affiliate member of the AIM Center International Council and his group.
Snippet - "We introduce for the first time a specific role for MITF in autophagy...
Join us at the annual AIM Center Symposium on Friday, February 22, 2019 for a day of plenary talks and workshops by leading autophagy scientists from around the world.
The symposia, hosted by Drs....
A new article from AIM Center scientists - "Beige adipocytes are present in white adipose tissue (WAT) and have thermogenic capacity to orchestrate substantial energy metabolism and counteract obesity...
The AIM Center is excited to reveal a new program in the works - The Vibrant Campus Initiative Program (VIP), which is currently being finalized. Make sure to follow us on twitter and periodically...
"Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico...
AIM center researchers, Drs. Meilian Liu and Xuexian Yang et all; have just published their findings in Nature - Scientific Reports on the"... previously unappreciated insight that obesity-associated...
AIM center researchers, Drs. Meilian Liu and Xuexian Yang et all; have just published their findings in Nature - Scientific Reports on the "... previously unappreciated insight that obesity-associated...