T cells play a vital role in eliminating pathogenic infections. To activate, naïve T cells search lymph nodes (LNs) for dendritic cells (DCs). Positioning and movement of T cells in LNs is influenced by chemokines including CCL21 as well as multiple cell types and structures in the LNs. Previous...
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Obesity promotes the development of insulin resistance and increases the incidence of colitis-associated cancer (CAC), but whether a blunted insulin action specifically in intestinal epithelial cells...
Liver macrophages (LMs) have been proposed to contribute to metabolic disease through secretion of inflammatory cytokines. However, anti-inflammatory drugs lead to only modest improvements in systemic...
One of world's most important autophagy gatherings
Congratulations to the AIM External Advisory Board Member, Beth Levine (beth.levine@utsouthwestern.edu), on successfully renewing her outstanding HHMI-funded research program in the Center for...
"Variants in Autophagy Related Genes and Clinical Characteristics in Melanoma: A Population-Based"
Based on their lobule location, hepatocytes display differential gene expression, including pericentral hepatocytes that surround the central vein, which are marked by Wnt-β-catenin signaling...







