News

04.02.2020

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells

A BioRxiv preprint in the BioRxiv COVID-19 collection: a study from the AIM center indicating that azithromycin and ciprofloxacin have effects similar to chloroquine in human respiratory epithelial cells. It’s up to clinicians to consider whether to resort to compassionate use of ciprofloxacin when there is a shortage of hydroxychloroquine or azithromcyn. Cautionary notes and disclaimer: (i) these are in vitro data and are yet to be tested in the clinic, and (ii) the study has not yet been peer...

Expression of Interest

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for competitive mentored PI (mPI) positions to be supported by the AIM P20 NIH award. 

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Latest

04.02.2020
Research

A BioRxiv preprint in the BioRxiv COVID-19 collection: a study from the AIM center indicating that azithromycin and ciprofloxacin have effects similar to chloroquine in human respiratory epithelial...

Metabolism Corner

02.17.2020
Metabolism

Continual efferocytic clearance of apoptotic cells (ACs) by macrophages prevents necrosis and promotes injury resolution. Macrophages take up arginine and ornithine from apoptotic cells and convert them into putrescine, augmenting continual efferocytosis and resolution of atherosclerosis.

02.17.2020
Metabolism

Macrophage mTORC1 senses protein in the diet in vivo and mediates dietary protein-driven atherosclerosis and lesion complexity by regulating mitophagy and mitochondria apoptosis.

Research Opportunities at AIM

At this time, we are accepting an Expression of Interest (EOI) by prospective candidates. The Autophagy Inflammation and Metabolism Center (AIM) is planning to conduct periodic searches for...

New postdoc position open in Dr. Vojo Deretic's laboratory to study Autophagy.