Role of circular RNAs in autophagy regulation and neuronal development and function in psychiatric disorders

Project Leader:
Dr. Nikolaos Mellios

Project Type: Primary

Abstract

Although ignored until recently for not complying with the central dogma of molecular biology, non-coding RNAs (ncRNAs) are emerging as important novel regulators of diverge cellular processes. The capacity of ncRNAs to engage in “molecular multitasking” positions them to link multiple genetic risk factors for polygenic human genetic disorders, such as psychiatric diseases, into functional networks.