BRD4, one of Bromodomain and extra-terminal domain (BET) proteins that bind to acetylated histones and transcription factors (TFs) and control cell-type-specific transcriptional programs, promotes...
News
Join us as the AIM Center kicks off the Tuesday AIM Seminar series for fall 2019!
Come and join the AIM Center's 2019 mini-symposium on September 6th, 2019, starting at 9:00am!
The AIM Center is proud to welcome Dr. Anne Simonsen, Keynote speaker, laureate, and King Olav V's...
The AIM center executive committee and staff plus the AIM center International Council of Affiliate members (ICAM) provide a summary on the 2nd year activities that took place at the center. https:/...
A natural dietary, microflora-derived metabolite Urolithin A was identified as a mitophagy activator to improve mitochondria function.
Reducing cholesterol in tumor tissue is a new strategy for restoring T cell function to enhance T cell-based immunotherapy.
Dr. Zbinden is visiting from Human Metabolome Technologies, to promote a new partnership with the AIM Center, at the University of New Mexico. HMT, founded in 2003, is a metabolomics company that...
ISOTT, the International Society on Oxygen Transport to Tissue, is comprised of 250 members worldwide. Its purpose is to further the understanding of all aspects of the processes involved in the...
Published:
| FULLTEXT 01.09.2019
Autophagy is a homeostatic and inducible process affecting multiple aspects of the immune system. This intrinsic cellular process is involved in MHC-antigen (Ag) presentation, inflammatory signaling, cytokine regulation, and cellular metabolism. In the context of T cell responses, autophagy has an...
Published:
| FULLTEXT 01.29.2019
T cells play a vital role in eliminating pathogenic infections. To activate, naïve T cells search lymph nodes (LNs) for dendritic cells (DCs). Positioning and movement of T cells in LNs is influenced by chemokines including CCL21 as well as multiple cell types and structures in the LNs. Previous...